Every week there are numerous scientific studies published. Heres a look at some of the more interesting ones.
Even Mild COVID-19 Induces Lasting Antibody Protection
A study out of Washington University School of Medicine in St. Louis found that months after recovering from mild COVID-19, patients maintained antibodies against the SARS-CoV-2 virus. And they believe that the specific cells that produce the antibodies should persist for a lifetime. They published their research in the journal Nature.
Last fall, there were reports that antibodies wane quickly after infection with the virus that causes COVID-19, and mainstream media interpreted that to mean that immunity was not love-lived, said senior author Ali Ellebedy, associate professor of pathology & immunology, of medicine and of molecular microbiology. But thats a misinterpretation of the data. Its normal for antibody levels to go down after acute infection, but they dont go down to zero; they plateau. Here, we found antibody-producing cells in people 11 months after first symptoms. These cells will live and produce antibodies for the rest of peoples lives. Thats strong evidence for long-lasting immunity.
Their research project track antibody levels in blood samples from COVID-19 survivors. They enrolled 77 participants who gave blood at three-month intervals beginning approximately a month after their initial infection. Only six of the patients had been hospitalized, with the rest having mild cases. They obtained bone marrow from 18 of the participants seven or eight months after the initial infections. Five returned four months later to provide a second bone marrow sample. They also collected bone marrow from 11 people who never had COVID-19. They found that blood antibody levels dropped quickly after infection and leveled off, although some antibodies were detectable 11 months post-infection. Of the 19 bone marrow samples in infected people, 15 contained antibody-producing cells that targeted the virus. They were still identified four months later in the five people who provided a second bone-marrow sample.
Why Our Skin Isnt Constantly Inflamed
Our skin is constantly exposed to environmental factors like bacteria, viruses and fungi, but our skin is not constantly inflamed. Researchers out of the University of California San Diego School of Medicine identified two enzymes that protect our skin and bodys overall health from these pathogens, while not triggering a constant immune and inflammatory response. The enzymes are called histone deacetylases (HDACs), and they inhibit the inflammatory response in the skin. The enzymes act on the chromosomes of specific skin cells that provide immune tolerance for the skin. Otherwise, said Richard Gallo, the Ima Gigli Distinguished Professor of Dermatology and chair of the Department of Dermatology at UCSD School of Medicine, wed have a constant rash on our skin.
Women with Osteoporosis and Low Bone Density at Increased Risk of Hearing Loss
Scientists at Brigham and Women's Hospital analyzed data from almost 144,000 women that they followed for up to 34 years as part of the Conservation of Hearing Study (CHEARS). They found that the risk of moderate or worse hearing loss was up to 40% in participants with osteoporosis or low bone density (LBD). They analyzed data from the Nurses Health Study (NHS) and NHS II, which were established in 1976 and 1989, respectively. The mechanisms are not clear, but they suggest that abnormal bone remodeling and changes in the pathways that maintain bone homeostasis might influence the bone that protects the nerves and hearing infrastructure or possibly change ion and fluid metabolism in the cochlea, the primary structure involved in hearing.
Smartwatch Data Might Predict Clinical Blood Tests
Smartwatches, such as the Apple Watch, Fitbit and Garmin, are capable of collecting a lot of information, including pulse, activity, sleep, oxygen levels, etc. Researchers at Duke University and the Stanford University School of Medicine published a study that used machine learning and data collected on smartwatches on 54 patients over three years and compared the data to traditional measurements collected during clinic visits, including heart rate, temperature, red and white blood cell count, glucose levels, and iron levels. They demonstrated there were multiple connections between the smartwatch data and clinical blood tests. Currently the smartwatch data isnt specific enough to accurately predict the precise number of blood cells, but they found enough correlations to act as proof-of-concept that physicians might someday be able to use wearable data to immediately get a picture of a patients overall health even before the clinical lab results are returned.
A Small Molecule to Rejuvenate the Alzheimers Brain
Researchers at the Netherlands Institute for Neuroscience (NIN) believe they have identified a small molecule that can rejuvenate the brain and fight memory loss in Alzheimers patients. Recent research identified adult-born cells in the hippocampus of elderly people. This suggested, broadly, that adult neurogenesisthe creation of new brain cells in adultscontinues through life. Adult neurogenesis sharply decreases in the brains of Alzheimers patients; but higher levels of adult neurogenesis was associated with better cognitive performance. They published their research in the journal Cell Stem Cell.
Seven years ago, while studying a small RNA molecule that is expressed in our brain, called microRNA-132, we came across a rather unexpected observation, said Evginia Salt, group leader at the NIN. This molecule, which we had previously found to be decreased in the brain of Alzheimers patients, seemed to regulate homeostasis of neural stem cells in the central nervous system.
At that point, it was thought that Alzheimers only affected mature neuronal cells, so the finding did not seem to have a role at that time in Alzheimers progression. They worked to determine if the microRNA-132 could regulate adult hippocampal neurogenesis in healthy and Alzheimers brain, working with mouse models, cultured human neural stem cells and postmortem human brain tissue. They discovered that the microRNA-132 was necessary for neurogenic processes in the adult hippocampus. What this means is it is a proof-of-concept for the therapeutic potential for adult neurogenesis in Alzheimers. Their next step is to evaluate the efficacy and safety of targeting microRNA-132 as a therapy for Alzheimers.
Read more:
Research Roundup: Even Mild COVID-19 Induces Lasting Antibody Protection and More - BioSpace
- 100 plus years of stem cell research20 years of ISSCR - PMC - March 26th, 2024
- Stem Cell Science and Human Research Studies Ahead of Cargo Arrival - NASA Blogs - February 18th, 2024
- Stem cell research project to launch into space - Fox Weather - January 24th, 2024
- Breakthrough in cancer research opening up stem cell therapy to more people. How you can get involved - 69News WFMZ-TV - January 20th, 2024
- Stem Cell Research Heading to the ISS on Axiom Mission 3 - ISS National Lab - January 18th, 2024
- No, Rep. Steve Scalise Didn't Vote Against Stem Cell Research From Which He Is Now Benefiting - The Dispatch - January 12th, 2024
- Applications are open for the Maryland Stem Cell Research Fund - Technical.ly - January 4th, 2024
- Global Stem Cell Therapy Market to Reach USD 928.6 Million by 2031: Says Allied Market Research - Yahoo Finance - November 19th, 2023
- Current state of stem cell-based therapies: an overview - PMC - November 3rd, 2023
- Dynamic Stem Cell Therapy Uncovers Research in Advance Regenrative Medicine - Yahoo Finance - November 3rd, 2023
- Research Fellow (Aging and Cancer Stem Cell Laboratory ... - Times Higher Education - October 15th, 2023
- Qkine Collaborates with the Cambridge Stem Cell Institute to Facilitate Same-Day Access to Key Research Products for Researchers at the Cambridge... - September 27th, 2023
- Stem cells: a comprehensive review of origins and emerging clinical ... - September 25th, 2023
- Stem Cell Research and Communicating Science | GBH - GBH News - September 20th, 2023
- Stem cell research reveals the earliest stages of a human life - SBS News - September 10th, 2023
- Stem Cell Therapy Market Size 2023 | Innovative Research Methodologies with Emerging Trends and Opportuni - Benzinga - September 10th, 2023
- Autologous Stem Cell and Non-Stem Cell Based Therapies Market Research, Current Trends, Key Industry Play - Benzinga - September 8th, 2023
- Stem Cell Therapy Market 2023 Business Statistics and Research ... - The Knox Student - August 28th, 2023
- Autologous Stem Cell Based Therapies Market Analysis, Research ... - Chatfield News-Record - July 19th, 2023
- Global Stem Cell Market Projected to Reach $14 Bn by 2028: Ken Research - Yahoo Finance - July 11th, 2023
- Theradaptive Awarded Manufacturing Assistance Grant by the Maryland Stem Cell Research Fund - Benzinga - July 10th, 2023
- Bionano Announces Presentation of OGM Utility Across Stem Cell Therapy Applications at the International Society for Stem Cell Research (ISSCR) Annual... - June 19th, 2023
- Sana Biotechnology Highlights Preclinical Data from Hypoimmune and Fusogen Platforms at the International Society for Stem Cell Research (ISSCR) 2023... - June 17th, 2023
- Induced Pluripotent Stem Cell (iPSC) Global Market Report 2023: Effective Research Programs Hold Key in Roll Out of Advanced iPSC Treatments - Yahoo... - June 17th, 2023
- Lung and heart stem cell research paves way for new COVID-19 treatments - Medical Xpress - June 14th, 2023
- Toxicology PhD student cultivating giant leaps in stem cell research ... - June 4th, 2023
- Harvard Stem Cell Institute (HSCI) - May 26th, 2023
- Findings may lead to improved insulin-secreting cells derived from stem ... - May 26th, 2023
- Cell Press: Stem Cell Reports - May 26th, 2023
- Stem cell research could enable blood to be made in other parts of the body - Medical Xpress - May 26th, 2023
- Construction of myocardial patch with mesenchymal stem cells and poly ... - May 22nd, 2023
- Cedars-Sinai to Send Stem Cells to the Space Station to Aid in the ... - May 22nd, 2023
- researchers expand human blood stem cells | Institute for Stem Cell ... - May 22nd, 2023
- A Look Inside Stem Cells Helps Create Personalized Regenerative ... - May 17th, 2023
- Exclusive Research Report on Msenchymal Stem Cell and Exosome Diagnostics and Therapies Market to Witness Comp - openPR - May 17th, 2023
- The Future of Stem Cell Research: Master of Science in ... - The Daily | Case Western Reserve University - May 10th, 2023
- Exclusive Research Report on Stem Cell Therapy for Diabetes and ... - Digital Journal - May 9th, 2023
- Aging melanocyte stem cells and gray hair | National Institutes of ... - May 5th, 2023
- Mouse hair turns gray when certain stem cells get stuck - May 5th, 2023
- Science-First Skincare Company Michal Morrison Secures Exclusive World-Wide License of Proprietary STEM6 Molecule, Supported by Over 25 Years of... - May 5th, 2023
- BioCentriq and panCELLa execute research agreement to study stem cell-derived Natural Killer cell expansi - Benzinga - May 3rd, 2023
- Hair turning gray? Study finds a stem cell 'glitch' may be the cause - May 1st, 2023
- Elevai Labs Announces Research Grant Award and Partnership to Better Characterize the 'Payload' of ELEVAI's Stem Cell-derived Exosomes - Yahoo Finance - April 27th, 2023
- Why does hair turn gray? A new study says 'stuck' stem cells may ... - NPR - April 27th, 2023
- Study advances understanding of how melanocyte stem cells work to color ... - April 21st, 2023
- Stem cell research and therapy legislation to be replaced, says ... - Bahamas Tribune - April 21st, 2023
- Stem Cell Research (journal) - Wikipedia - April 21st, 2023
- Scientists Are About to Try to Create Stem Cells in Space - April 21st, 2023
- Stem Cell Research & Therapy | Articles - BioMed Central - April 16th, 2023
- Stem Cell Junk Yards Reveal a New Clue About Aging | WIRED - April 16th, 2023
- Global Stem Cells Market Research Report 2023: Implications - April 16th, 2023
- Stem cell research can help people with hard- | EurekAlert! - April 16th, 2023
- University Of Edinburgh's stem cell research gets funding boost - India Education Diary - April 14th, 2023
- Two major stem cell research projects supported with more than ... - University of California, Santa Cruz - April 8th, 2023
- Cancer detection predicts tumors before they form: discovery - March 29th, 2023
- Stem cell therapy: a potential cure for hearing loss? - March 29th, 2023
- Turkey's Only Stem Cell Production Application and Research Center - Expat Guide Turkey - March 24th, 2023
- Stem Cell Research Article, Embryonic Cells Information, Cell Therapy ... - March 24th, 2023
- Scientists create mice with cells from 2 males for 1st time - March 19th, 2023
- QBRI concludes stem cells symposium - Gulf Times - March 17th, 2023
- 2020 California Proposition 14 - Wikipedia - March 17th, 2023
- Stem Cell Reports | Journal | ScienceDirect.com by Elsevier - March 17th, 2023
- Stem cell therapy MSC-NP found to ease inflammatory activity of brain ... - March 12th, 2023
- Stem Cell Research | Office of Research Compliance | SIU - March 12th, 2023
- Heart disease study shows hope for stem cell treatment - March 4th, 2023
- Stem cells drive antler regeneration | Science - March 4th, 2023
- Stem Cell Research: Argumentative Essay - Free Essay Example - Edubirdie - March 4th, 2023
- Stem Cell Research | Thermo Fisher Scientific - US - March 4th, 2023
- Stem cell controversy - Wikipedia - February 28th, 2023
- National Institutes of Health grant funds interdisciplinary ... - February 27th, 2023
- Research Associate in Cancer Stem Cell Research job with ... - Times Higher Education - February 25th, 2023
- Pioneering Stem Cell Research Conference at The Aga Khan ... - The Aga Khan University - February 25th, 2023
- Scientists grapple with ethics of stem cell research - STAT - February 17th, 2023
- Research Associate in Stem Cell Neurobiology job with KINGS ... - Times Higher Education - January 30th, 2023
- Stem cells: past, present, and future | Stem Cell Research & Therapy ... - January 12th, 2023
- Edu Thesis & Essay: Stem cell research outline top writers online! - January 12th, 2023
- Stem Cell Biology Research Program | Johns Hopkins Institute for Cell ... - January 5th, 2023
- Stem cell population identified is vital for bone regeneration: Research - ThePrint - January 5th, 2023
- Leading scientist 'blown away' by UAE advances in stem cell research - The National - December 15th, 2022
- The Stem Cell Assay Market Is Set To Grow At A 20% Annual Rate, Due To The High Prevalence Of Chronic Diseases As Per The Business Research Company's... - December 13th, 2022
Recent Comments