Neurologic and Cognitive Outcomes in Sickle Cell Disease from Infancy through Adolescence – AAP News

Children with sickle cell disease (SCD) are at risk for neurologic and cognitive complications beginning in early childhood. Current treatment for SCD focuses on primary prevention of complications, such as hydroxyurea for prevention of pain and acute chest syndrome, and chronic transfusion therapy for children who are at high risk for strokes. In this article, the prevalence, pathophysiology, and available interventions to prevent and treat neurologic and cognitive complications of SCD will be reviewed.

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Neurologic and Cognitive Outcomes in Sickle Cell Disease from Infancy through Adolescence - AAP News