Dublin, April 13, 2021 (GLOBE NEWSWIRE) -- The "Global Induced Pluripotent Stem Cell (iPS Cell) Industry Report 2021" report has been added to ResearchAndMarkets.com's offering.
The main objectives of this report are to describe the current status of iPSC research, patents, funding events, industry partnerships, biomedical applications, technologies, and clinical trials for the development of iPSC-based therapeutics.
Since the discovery of induced pluripotent stem cells (iPSCs) a large and thriving research product market has grown into existence, largely because the cells are non-controversial and can be generated directly from adult cells. It is clear that iPSCs represent a lucrative market segment because methods for commercializing this cell type are expanding every year and clinical studies investigating iPSCs are swelling in number.
Therapeutic applications of iPSCs have surged in recent years. 2013 was a landmark year in Japan because it saw the first cellular therapy involving the transplant of iPSCs into humans initiated at the RIKEN Center in Kobe, Japan. Led by Masayo Takahashi of the RIKEN Center for Developmental Biology (CDB), it investigated the safety of iPSC-derived cell sheets in patients with macular degeneration.
In another world-first, Cynata Therapeutics received approval in 2016 to launch the world's first formal clinical trial of an allogeneic iPSC-derived cell product (CYP-001) for the treatment of GvHD.
Riding the momentum within the CAR-T field, Fate Therapeutics is developing FT819, its "off-the-shelf" iPSC-derived CAR-T cell product candidate. Numerous physician-led studies using iPSCs are also underway in Japan, a leading country for basic and applied iPSC applications.
iPS Cell Market Competitors
Today, FUJIFILM CDI has emerged as one of the largest commercial players within the iPSC sector. FUJIFILM CDI was founded in 2004 by Dr. James Thomson at the University of Wisconsin-Madison, who in 2007 derived iPSC lines from human somatic cells for the first time ever. The feat was accomplished simultaneously by Dr. Shinya Yamanaka's lab in Japan.
In 2009, ReproCELL, a company established as a venture company originating from the University of Tokyo and Kyoto University, made iPSC products commercially available for the first time with the launch of its human iPSC-derived cardiomyocytes, which it called ReproCario.
A European leader within the iPSC market is Ncardia, formed through the merger of Axiogenesis and Pluriomics. Founded in 2001, Axiogenesis initially focused on generating mouse embryonic stem cell-derived cells and assays, but after Yamanaka's iPSC technology became available, it became the first European company to license it in 2010. Ncardia's focus is on preclinical drug discovery and drug safety through the development of functional assays using human neuronal and cardiac cells.
In total, at least 68 distinct market competitors now offer various types of iPSC products, services, technologies and therapies.
iPS Cell Commercialization
Methods of commercializing induced pluripotent stem cells (iPSCs) are diverse and continue to expand. iPSC cell applications include, but are not limited to:
Since the discovery of iPSC technology in 2006, significant progress has been made in stem cell biology and regenerative medicine. New pathological mechanisms have been identified and explained, new drugs identified by iPSC screens are in the pipeline, and the first clinical trials employing human iPSC-derived cell types have been initiated.
Key Topics Covered:
1. REPORT OVERVIEW1.1 Statement of the Report1.2 Executive Summary
2. INTRODUCTION2.1 Discovery of iPSCs2.2 Barriers in iPSC Application2.3 Timeline and Cost of iPSC Development2.4 Current Status of iPSCs Industry2.4.1 Share of iPSC-based Research within the Overall Stem Cell Industry2.4.2 Major Focuses of iPSC Companies2.4.3 Commercially Available iPSC-Derived Cell Types2.4.4 Relative Use of iPSC-Derived Cell Types in Toxicology Testing Assays2.4.5 Toxicology/Safety Testing Assays using iPSC-Derived Cell Types2.5 Currently Available iPSC Technologies2.6 Advantages and Limitations of iPSCs Technology
3. HISTORY OF INDUCED PLURIPOTENT STEM CELLS (IPSCS)3.1 First iPSC generation from Mouse Fibroblasts, 20063.2 First Human iPSC Generation, 20073.3 Creation of CiRA, 20103.4 First High-Throughput screening using iPSCs, 20123.5 First iPSCs Clinical Trial Approved in Japan, 20133.6 The First iPSC-RPE Cell Sheet Transplantation for AMD, 20143.7 EBiSC Founded, 20143.8 First Clinical Trial using Allogeneic iPSCs for AMD, 20173.9 Clinical Trials for Parkinson's disease using Allogeneic iPSCs, 20183.10 Commercial iPSC Plant SMaRT Established, 20183.11 First iPSC Therapy Center in Japan, 2019
4. RESEARCH PUBLICATIONS ON iPSCS4.1 Categories of Research Publications4.2 Percent Share of Published Articles by Disease Type4.3 Number of Articles by Country
5. IPSCS: PATENT LANDSCAPE5.1 Timeline and Status of Patents5.2 Patent Filing Destinations5.2.1 Patent Applicant's Origin5.2.2 Top Ten Global Patent Applicants5.2.3 Collaborating Applicants of Patents5.3 Patent Application Trends iPSC Preparation Technologies5.4 Patent Application Trends in iPSC Differentiation Technologies5.5 Patent Application Trends in Disease-Specific Cell Technologies
6. CLINICAL TRIALS INVOLVING iPSCS6.1 Current Clinical Trials Landscape6.1.1 Clinical Trials Involving iPSCs by Major Diseases6.1.2 Clinical Trials Involving iPSCs by Country
7. FUNDING FOR iPSCs7.1 Value of NIH Funding for iPSCs7.1.1 NHI's Intended Funding Through its Component Organizations in 20207.1.2 NIH Funding for Select Universities for iPSC Studies7.2 CIRM Funding for iPSCs
8. GENERATION OF INDUCED PLURIPOTENT STEM CELLS: AN OVERVIEW8.1 Reprogramming Factors8.2 Overview of Four Key Methods of Gene Delivery8.3 Comparative Effectiveness of Different Vector Types8.4 Genome Editing Technologies in iPSCs Generation
9. HUMAN iPSC BANKING9.1 Cell Sources for iPSCs Banking9.2 Reprogramming methods used in iPSC Banking9.3 Workflow in iPSC Banks9.4 Existing iPSC Banks
10. BIOMEDICAL APPLICATIONS OF iPSCS10.1 iPSCs in Basic Research10.2 iPSCs in Drug Discovery10.3 iPSCs in Toxicology Studies10.4 iPSCs in Disease Modeling10.5 iPSCs within Cell-Based Therapies
11. OTHER NOVEL APPLICATIONS OF iPSCS11.1 iPSCs in Tissue Engineering11.2 iPSCs in Animal Conservation11.3 iPSCs and Cultured Meat
12. DEAL-MAKING WITHIN THE iPSC SECTOR12.1 License Agreement between FUJIFILM Cellular Dynamics and Sana12.2 Century Therapeutics Closes $160 Million Series C Financing12.3 Bluerock Gains Access to Ncardia's iPSCs-derived Cardiomyocytes12.4 Fate Therapeutics' Deal with Janssen Biotech12.5 Century Therapeutics Acquires Empirica Therapeutics12.6 $250 Million Raised by Century Theraputics12.7 BlueRock Therapeutics Launched with $225 Million12.8 Collaboration between Allogene Therapeutics and Notch Therapeutics12.9 Acquisition of Semma Therapeutics by Vertex Therapeutics12.10 Evotec's Extended Collaboration with BMS12.11 Licensing Agreement between Allele Biotechnology and Astellas12.12 Codevelopment Agreement between Allele & SCM Lifesciences12.13 Fate Therapeutics Signs $100 Million Deal with Janssen12.14 Allele's Deal with Alpine Biotherapeutics12.15 Editas and BlueRock's Development Agreement
13. MARKET OVERVIEW13.1 Global Market for iPSCs by Geography13.2 Global Market for iPSCs by Technology13.3 Global Market for iPSCs by Biomedical Application13.4 Global Market for iPSCs by Cell Types3.5 Market Drivers13.6 Market Restraints
14. COMPANY PROFILES
For more information about this report visit https://www.researchandmarkets.com/r/d2jcbt
Here is the original post:
- 100 plus years of stem cell research20 years of ISSCR - PMC - March 26th, 2024
- Stem Cell Science and Human Research Studies Ahead of Cargo Arrival - NASA Blogs - February 18th, 2024
- Stem cell research project to launch into space - Fox Weather - January 24th, 2024
- Breakthrough in cancer research opening up stem cell therapy to more people. How you can get involved - 69News WFMZ-TV - January 20th, 2024
- Stem Cell Research Heading to the ISS on Axiom Mission 3 - ISS National Lab - January 18th, 2024
- No, Rep. Steve Scalise Didn't Vote Against Stem Cell Research From Which He Is Now Benefiting - The Dispatch - January 12th, 2024
- Applications are open for the Maryland Stem Cell Research Fund - Technical.ly - January 4th, 2024
- Global Stem Cell Therapy Market to Reach USD 928.6 Million by 2031: Says Allied Market Research - Yahoo Finance - November 19th, 2023
- Current state of stem cell-based therapies: an overview - PMC - November 3rd, 2023
- Dynamic Stem Cell Therapy Uncovers Research in Advance Regenrative Medicine - Yahoo Finance - November 3rd, 2023
- Research Fellow (Aging and Cancer Stem Cell Laboratory ... - Times Higher Education - October 15th, 2023
- Qkine Collaborates with the Cambridge Stem Cell Institute to Facilitate Same-Day Access to Key Research Products for Researchers at the Cambridge... - September 27th, 2023
- Stem cells: a comprehensive review of origins and emerging clinical ... - September 25th, 2023
- Stem Cell Research and Communicating Science | GBH - GBH News - September 20th, 2023
- Stem cell research reveals the earliest stages of a human life - SBS News - September 10th, 2023
- Stem Cell Therapy Market Size 2023 | Innovative Research Methodologies with Emerging Trends and Opportuni - Benzinga - September 10th, 2023
- Autologous Stem Cell and Non-Stem Cell Based Therapies Market Research, Current Trends, Key Industry Play - Benzinga - September 8th, 2023
- Stem Cell Therapy Market 2023 Business Statistics and Research ... - The Knox Student - August 28th, 2023
- Autologous Stem Cell Based Therapies Market Analysis, Research ... - Chatfield News-Record - July 19th, 2023
- Global Stem Cell Market Projected to Reach $14 Bn by 2028: Ken Research - Yahoo Finance - July 11th, 2023
- Theradaptive Awarded Manufacturing Assistance Grant by the Maryland Stem Cell Research Fund - Benzinga - July 10th, 2023
- Bionano Announces Presentation of OGM Utility Across Stem Cell Therapy Applications at the International Society for Stem Cell Research (ISSCR) Annual... - June 19th, 2023
- Sana Biotechnology Highlights Preclinical Data from Hypoimmune and Fusogen Platforms at the International Society for Stem Cell Research (ISSCR) 2023... - June 17th, 2023
- Induced Pluripotent Stem Cell (iPSC) Global Market Report 2023: Effective Research Programs Hold Key in Roll Out of Advanced iPSC Treatments - Yahoo... - June 17th, 2023
- Lung and heart stem cell research paves way for new COVID-19 treatments - Medical Xpress - June 14th, 2023
- Toxicology PhD student cultivating giant leaps in stem cell research ... - June 4th, 2023
- Harvard Stem Cell Institute (HSCI) - May 26th, 2023
- Findings may lead to improved insulin-secreting cells derived from stem ... - May 26th, 2023
- Cell Press: Stem Cell Reports - May 26th, 2023
- Stem cell research could enable blood to be made in other parts of the body - Medical Xpress - May 26th, 2023
- Construction of myocardial patch with mesenchymal stem cells and poly ... - May 22nd, 2023
- Cedars-Sinai to Send Stem Cells to the Space Station to Aid in the ... - May 22nd, 2023
- researchers expand human blood stem cells | Institute for Stem Cell ... - May 22nd, 2023
- A Look Inside Stem Cells Helps Create Personalized Regenerative ... - May 17th, 2023
- Exclusive Research Report on Msenchymal Stem Cell and Exosome Diagnostics and Therapies Market to Witness Comp - openPR - May 17th, 2023
- The Future of Stem Cell Research: Master of Science in ... - The Daily | Case Western Reserve University - May 10th, 2023
- Exclusive Research Report on Stem Cell Therapy for Diabetes and ... - Digital Journal - May 9th, 2023
- Aging melanocyte stem cells and gray hair | National Institutes of ... - May 5th, 2023
- Mouse hair turns gray when certain stem cells get stuck - May 5th, 2023
- Science-First Skincare Company Michal Morrison Secures Exclusive World-Wide License of Proprietary STEM6 Molecule, Supported by Over 25 Years of... - May 5th, 2023
- BioCentriq and panCELLa execute research agreement to study stem cell-derived Natural Killer cell expansi - Benzinga - May 3rd, 2023
- Hair turning gray? Study finds a stem cell 'glitch' may be the cause - May 1st, 2023
- Elevai Labs Announces Research Grant Award and Partnership to Better Characterize the 'Payload' of ELEVAI's Stem Cell-derived Exosomes - Yahoo Finance - April 27th, 2023
- Why does hair turn gray? A new study says 'stuck' stem cells may ... - NPR - April 27th, 2023
- Study advances understanding of how melanocyte stem cells work to color ... - April 21st, 2023
- Stem cell research and therapy legislation to be replaced, says ... - Bahamas Tribune - April 21st, 2023
- Stem Cell Research (journal) - Wikipedia - April 21st, 2023
- Scientists Are About to Try to Create Stem Cells in Space - April 21st, 2023
- Stem Cell Research & Therapy | Articles - BioMed Central - April 16th, 2023
- Stem Cell Junk Yards Reveal a New Clue About Aging | WIRED - April 16th, 2023
- Global Stem Cells Market Research Report 2023: Implications - April 16th, 2023
- Stem cell research can help people with hard- | EurekAlert! - April 16th, 2023
- University Of Edinburgh's stem cell research gets funding boost - India Education Diary - April 14th, 2023
- Two major stem cell research projects supported with more than ... - University of California, Santa Cruz - April 8th, 2023
- Cancer detection predicts tumors before they form: discovery - March 29th, 2023
- Stem cell therapy: a potential cure for hearing loss? - March 29th, 2023
- Turkey's Only Stem Cell Production Application and Research Center - Expat Guide Turkey - March 24th, 2023
- Stem Cell Research Article, Embryonic Cells Information, Cell Therapy ... - March 24th, 2023
- Scientists create mice with cells from 2 males for 1st time - March 19th, 2023
- QBRI concludes stem cells symposium - Gulf Times - March 17th, 2023
- 2020 California Proposition 14 - Wikipedia - March 17th, 2023
- Stem Cell Reports | Journal | ScienceDirect.com by Elsevier - March 17th, 2023
- Stem cell therapy MSC-NP found to ease inflammatory activity of brain ... - March 12th, 2023
- Stem Cell Research | Office of Research Compliance | SIU - March 12th, 2023
- Heart disease study shows hope for stem cell treatment - March 4th, 2023
- Stem cells drive antler regeneration | Science - March 4th, 2023
- Stem Cell Research: Argumentative Essay - Free Essay Example - Edubirdie - March 4th, 2023
- Stem Cell Research | Thermo Fisher Scientific - US - March 4th, 2023
- Stem cell controversy - Wikipedia - February 28th, 2023
- National Institutes of Health grant funds interdisciplinary ... - February 27th, 2023
- Research Associate in Cancer Stem Cell Research job with ... - Times Higher Education - February 25th, 2023
- Pioneering Stem Cell Research Conference at The Aga Khan ... - The Aga Khan University - February 25th, 2023
- Scientists grapple with ethics of stem cell research - STAT - February 17th, 2023
- Research Associate in Stem Cell Neurobiology job with KINGS ... - Times Higher Education - January 30th, 2023
- Stem cells: past, present, and future | Stem Cell Research & Therapy ... - January 12th, 2023
- Edu Thesis & Essay: Stem cell research outline top writers online! - January 12th, 2023
- Stem Cell Biology Research Program | Johns Hopkins Institute for Cell ... - January 5th, 2023
- Stem cell population identified is vital for bone regeneration: Research - ThePrint - January 5th, 2023
- Leading scientist 'blown away' by UAE advances in stem cell research - The National - December 15th, 2022
- The Stem Cell Assay Market Is Set To Grow At A 20% Annual Rate, Due To The High Prevalence Of Chronic Diseases As Per The Business Research Company's... - December 13th, 2022
Recent Comments