New stem cell identified by Sanford Burnham Prebys researchers offers hope to people with rare liver disease – Newswise

Newswise LA JOLLA, CALIF. October 11 Researchers from Sanford Burnham Prebys have discovered a new source of stem cells just outside the liver that could help treat people living with Alagille syndrome, a rare, incurable genetic disorder in which the bile ducts of the liver are absent, leading to severe liver damage and death

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Repurposed Drug Reverses Signs of Alzheimers in Mice, Human Cells – The Scientist

Bumetanide, a drug already approved to treat swelling associated with conditions such as heart failure, improved performance on cognitive tests and reduced the buildup of amyloid plaques in mice with an Alzheimers-like condition, researchers report. Furthermore, in cultured human neurons derived from stem cells, bumetanide reversed gene expression changes associated with Alzheimers, and the electronic health records of millions of patients point to a link between the drug and reduced odds of being diagnosed with the disease. On the basis of these results, published this week (October 10) in Nature Aging, Gladstone Institutes neurobiologist and study coauthor Yadong Huang tells STAT that he and his team are now pursuing a clinical trial to test the drug in human patients with at least one copy of the APOE4 variant, a well-known risk factor for the disease

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Autologous HSCT Continues to Show Sustained Benefit in MCL, But Targeted Therapies May Challenge its Role as Standard Frontline Treatment -…

A post-hoc analysis of a phase 3 trial published in The Lancet Haematology demonstrated that autologous hematopoietic stem-cell transplantation (HSCT) induced superior long-term benefit in patients with mantle cell lymphoma (MCL) in comparison with interferon alfa.1 The sustained efficacy associated with HSCT supports its role as standard frontline treatment for this population, however, new targeted therapies may potentially challenge that role.

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Bartolo Coln, Winner Of The Cy Young, Wins Lawsuit In Case Of Stem Cell Treatment To Which He Was Subjected Before His Return To The Major Leagues. -…

11 October 2021 Guzman Ariza Attorneys At Law To print this article, all you need is to be registered or login on Mondaq.com. The Second Chamber of the Civil and Commercial Chamber of theCourt of Appeal of Santiago annulled the sentence issued by thefirst-degree court that condemned the winning pitcher of the CyYoung Bartolo Coln to the payment of US $ 4.5 million, foralleged compensation on future earnings after his return to theMajor Leagues, to the Dominican doctors who assisted him in thetreatment of stem cells in the tissues of his right shoulder.

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