Capping Medicare Part B payments will limit outpatient access to CAR-T – STAT

The revolutionary life-extending approach to treating cancer known as CAR-T is under threat from a quotidian source: policy proposals to limit Medicare reimbursement in the outpatient setting to the average sales price of the treatment plus a small addition for overhead. Chimeric antigen receptor T-cell (CAR-T) therapies have been changing the cancer treatment landscape. These one-time customized treatments created from an individuals own T cells represent a significant advancement in treatment.

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Treating Patients with High-Risk Myelodysplastic Syndrome – Targeted Oncology

Naval Daver, MD: Each year, of all the patients with MDS [myelodysplastic syndrome] in the United States, about 55% to 60% will present with a higher-risk MDS. We generally consider, using the IPSS-R [Revised International Prognostic Scoring System], anybody who has intermediate, high, or very high, any of those 3 categories, to be among the higher-risk MDS population. For this patient population, the goals of treatment are 2-fold

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FDA Issues Draft Guidance on Donor Eligibility and Manufacturing of Cellular Therapies for Animals | FDA – FDA.gov

For Immediate Release: September 22, 2021 Today, the U.S Food and Drug Administration issued for public comment two draft guidance documents that, if finalized, will help manufacturers of animal cells, tissues, and cell- and tissue-based products (ACTPs) understand current good manufacturing practice requirements (CGMPs) for new animal drugs under the Federal Food, Drug, and Cosmetic Act (FD&C Act). CGMPs help prevent contamination and help ensure ACTP quality. If finalized, the recommendations are intended to support the development of promising and innovative products that can benefit animal health

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Stem Rx Bioscience Solutions successfully use cell-based therapy for age-related macular degeneration and restoration of vision – Financial Express

Navi Mumbai based Stem Rx Bioscience Solutions Pvt Ltd successfully restored the eyesight of a 58-year-old man with age-related macular degeneration (AMD) by cell-based therapy. Loss of vision caused by AMD can be restored by using the patients own stem cells to repair damaged tissue and cure the disease. Loss of vision has a huge impact on a persons life, but many of the disorders that cause blindness are currently difficult or impossible to treat, Informed Dr

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Repeated injury to the epithelial tissue of airways causes "biological aging" of stem cells – News-Medical.net

Are prematurely aged or overworked stem cells a significant factor in chronic lung disease? Findings of a study just released in STEM CELLS Translational Medicine (SCTM) say this is likely so. The study determined that repeated injury to the epithelial tissue of the airways causes "biological aging" of the stem cells located there

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Revival of the cell and gene therapy field opens new avenues for repairing the Parkinsonian brain – News-Medical.Net

After several decades of pre-clinical development, cell- and gene-based therapies for Parkinson's disease (PD) are now actively being explored. In this special supplement to the Journal of Parkinson's Disease on "Repairing the Parkinsonian Brain," experts highlight some of the current strategies being pursued to restore lost function and replace what is lost in the PD brain, with special emphasis on the challenges associated with translating advanced therapeutic approaches into pioneering clinical trials.

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Scientists Awarded The Albany Prize, America’s Most Distinguished Prize in Medicine, for Research Leading to Covid-19 Vaccines – Albany Medical Center

Scientists Awarded The Albany Prize, Americas Most Distinguished Prize in Medicine, for Research Leading to Covid-19 Vaccines September 21, 2021 - Albany, NY Threepioneeringscientists,whosediscoveries haveled toinnovativeadvances in medicine, including the vaccines for Covid-19, were presented with the 2021 Albany Medical Center Prize in Medicine and Biomedical Research, celebrating its 20th anniversary, today during a ceremony in Albany, New York. The recipients are: Dr. Grahams research investigated optimal immunogen structure to induce potent neutralizing responses

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