How Bone Marrow and Stem Cells are Collected | BMT Infonet

If you are providing the blood stem cells for a transplant, they will either be collected from your bloodstream (peripheral blood) or from your bone marrow. The largest concentration of blood stem cells is in your bone marrow. However, the blood stem cells can be moved or "mobilized" out of the bone marrow into the bloodstream (peripheral blood) where they can be easily collected.

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Wealth of Newer Treatment Options Span the Scope of Multiple Myeloma and Amyloidosis – OncLive

Tomer Mark, MD, discusses the emerging role of minimal residual disease as a surrogate end point in multiple myeloma, treatment selection for patients with newly diagnosed, early relapsed, and late relapsed disease, and the importance of daratumumab being introduced to the treatment paradigm of amyloidosis. Treatment selection for patients with newly diagnosed, early relapsed, and late relapsed multiple myeloma requires consideration of patient-, disease-, and treatment-related factors, said Tomer Mark, MD, who added that the need for minimal residual disease (MRD) as a surrogate end point for survival is stronger now with optimal sequencing strategies remaining uncertain. Multiple myeloma is moving very fast right now.

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Trial of Cell Therapy to Raise HbF Levels Showing Potential, But… – Sickle Cell Anemia News

Sangamo Therapeuticsis assuming all rights to SAR445136, an investigational gene-edited cell therapy co-developed withSanofiand now in a Phase 1/2 trial in adults with severe sickle cell disease (SCD). Early trial data support the therapys safety and tolerability, and its effectiveness atraising levels of fetal hemoglobin in patients, the companies have announced. Sanofi had been leading the Phase 1/2 PRECIZN-1 trial (NCT03653247) with the therapy under that companys assigned name of BIVV003 as part of a cooperation agreement between the two pharmas

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The Fusion of mRNA and Immunotherapy – NEO.LIFE

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